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                <text>Multigenerational Legacies of Trauma of American Indians</text>
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            <text>&lt;a href="https://doi.org/10.1111/acer.15521"&gt;https://doi.org/10.1111/acer.15521&lt;/a&gt;</text>
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            <text>Jessica Hanson, Carolyn Noonan, Kyra Oziel, Karen Little Wounded, Serea Darnell, Robert Rosenman, Marcia O'Leary, Richard MacLehose, Michelle Sarche, Dedra Buchwald</text>
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            <text>Vol. 49</text>
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            <text>Wiley-Blackwell</text>
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            <text>Alcohol, Clinical and Experimental Research</text>
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            <text>2025</text>
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            <text>29937175</text>
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            <text>English</text>
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            <text>Background&#13;
Prevention of alcohol-exposed pregnancy (AEP) involves reducing risky alcohol consumption among women at-risk for pregnancy, using effective contraception among women drinking at risky levels to prevent pregnancy, or both. This study presents the outcomes of a randomized controlled trial assessing the efficacy of Native CHOICES, a culturally tailored adaptation of the CHOICES intervention, among American Indian/Alaska Native (AI/AN) women.&#13;
&#13;
Methods&#13;
AI/AN women aged 18–44 who were at-risk for an AEP were randomly assigned in a 1:1 ratio to either the Native CHOICES intervention or a waitlist control group. Native CHOICES comprised two sessions of motivational interviewing and an elective contraception counseling session. Data were collected at baseline, and 6 weeks, 3 months, and 6 months postbaseline. Due to the pandemic, the intervention was at times delivered remotely.&#13;
&#13;
Results&#13;
A total of 404 women participated: 199 in the control group and 205 in the intervention group. Sixty-seven percent of the intervention group received the intervention in-person, and 33% participated by telephone or video call. Sixty-four percent of women completed all follow-up visits. At the six-month follow-up, the intervention did not demonstrate a significant impact on AEP risk compared with the control arm when analyzing all the data (RR = 0.94; 95% confidence interval [CI]: 0.83–1.07). However, an exploratory subgroup analysis showed evidence of a reduction in AEP risk among participants who completed the study in-person before the COVID-19 pandemic (RR = 0.79; 95% CI: 0.63–0.98), which was not observed during or after the pandemic (RR = 1.06; 95% CI: 0.91–1.24).&#13;
&#13;
Conclusions&#13;
The Native CHOICES intervention did not show evidence of effectiveness overall. However, exploratory analyses offer some evidence that the intervention was effective prior to the pandemic.</text>
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            <text>Julia Arizono</text>
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              <text>A Randomized Controlled Trial of Native CHOICES: Impact on alcohol-exposed pregnancy risk reduction among American Indian and Alaska Native women</text>
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              <text>Pregnant women--Alcohol use--Prevention</text>
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      <name>Alcohol Abuse</name>
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      <name>COVID-19</name>
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      <name>Indigenous peoples</name>
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      <name>Pregnancy</name>
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      <name>Women</name>
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