https://library.icmglt.org/files/original/0443389cd9bad9c91adf4568813ffc14.jpg 33b735b5c89c147c289d73d21e5313bb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Holocaust, 1939-1945 Electronic Resource View Source <a href="https://doi.org/10.1016/j.psyneuen.2014.06.001">https://doi.org/10.1016/j.psyneuen.2014.06.001</a> Document Type Journal article Author(s) Amy L Lehrner, Heather N Bader, Louri Makotkine, Jonathan R Seckl, Linda M Bierer, Nikolaos P Daskalakis, Rachel Yehuda Volume Vol. 48 Journal Name Psychoneuroendocrinology Publication Date 2014 Language English Access Restricted Access Abstract Adult offspring of Holocaust survivors comprise an informative cohort in which to study intergenerational transmission of the effects of trauma exposure. Lower cortisol and enhanced glucocorticoid sensitivity have been previously demonstrated in Holocaust survivors with PTSD, and in offspring of Holocaust survivors in association with maternal PTSD. In other work, reduction in the activity of the enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD-2), which inactivates cortisol, was identified in Holocaust survivors in comparison to age-matched, unexposed Jewish controls. Therefore, we investigated glucocorticoid metabolism in offspring of Holocaust survivors to evaluate if similar enzymatic decrements would be observed that might help to explain glucocorticoid alterations previously shown for Holocaust offspring. Cataloger Kristen Walker Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Elevation of 11β-Hydroxysteroid Dehydrogenase Type 2 Activity in Holocaust Survivor Offspring: Evidence for an Intergenerational Effect of Maternal Trauma Exposure Subject The topic of the resource Endocrinology Children of Holocaust Survivors Genocide Holocaust Holocaust Exposure Intergenerational Transmission of Trauma Jewish Identity Mental Health Mental Illness Offspring Psychological Trauma Reconciliation